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1

Design and evaluation of azaindole-substituted N-hydroxypyridones as glyoxalase I inhibitors

Chiba, Takashi, Ohwada, Jun, Sakamoto, Hiroshi, Kobayashi, Takamitsu, Fukami, Takaaki A., Irie, Machiko, Miura, Takaaki, Ohara, Kazuhiro, Koyano, Hiroshi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 712 KB

english, 2012

2

Treatment Outcome of Nonclostridial Gas Gangrene at a Level 1 Trauma Center

Takahira, Naonobu, Shindo, Masateru, Tanaka, Keiji, Soma, Kazui, Ohwada, Takashi, Itoman, Moritoshi

Journal:

Journal of Orthopaedic Trauma

Year:

2002

Language:

english

File:

PDF, 712 KB

english, 2002

3

Association of CDKN2A (p16)/CDKN2B (p15) alterations and homozygous chromosome arm 9p deletions in human lung carcinoma

Kunihiro Hamada, Takashi Kohno, Masashi Kawanishi, Susumu Ohwada, Jun Yokota

Journal:

Genes, Chromosomes and Cancer

Year:

1998

Language:

english

File:

PDF, 173 KB

english, 1998

4

Two regions of homozygous deletion clusters at chromosome band 9p21 in human lung cancer

Kunihiro Hamada, Takashi Kohno, Mina Takahashi, Masaaki Yamazaki, Hiroyuki Tashiro, Chiyo Sugawara, Susumu Ohwada, Yoshitaka Sekido, John D. Minna, Jun Yokota

Journal:

Genes, Chromosomes and Cancer

Year:

2000

Language:

english

File:

PDF, 268 KB

english, 2000

5

Conduction system abnormalities in rat embryos induced by maternal hyperthermia

Naoyoshi Aoyama, Shohei Yamashina, Robert E. Poelmann, Adriana C. Gittenberger-De Groot, Tohru Izumi, Kazui Soma, Takashi Ohwada

Journal:

The Anatomical Record Advances in Integrative Anatomy and Evolutionary Biology

Year:

2002

Language:

english

File:

PDF, 3.82 MB

english, 2002

6

Genetic and epigenetic alterations of the candidate tumor-suppressor gene MYO18B, on chromosome arm 22q, in colorectal cancer

Tetsuhiro Nakano, Masachika Tani, Michiho Nishioka, Takashi Kohno, Ayaka Otsuka, Susumu Ohwada, Jun Yokota

Journal:

Genes, Chromosomes and Cancer

Year:

2005

Language:

english

File:

PDF, 261 KB

english, 2005

7

Novel BK channel openers containing dehydroabietic acid skeleton: Structure–activity relationship for peripheral substituents on ring C

Yong-Mei Cui, Eriko Yasutomi, Yuko Otani, Takashi Yoshinaga, Katsutoshi Ido, Kohei Sawada, Tomohiko Ohwada

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 223 KB

english, 2008

8

Design, synthesis, and characterization of BK channel openers based on oximation of abietane diterpene derivatives

Yong-Mei Cui, Eriko Yasutomi, Yuko Otani, Katsutoshi Ido, Takashi Yoshinaga, Kohei Sawada, Tomohiko Ohwada

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.86 MB

english, 2010

9

Design, synthesis and characterization of podocarpate derivatives as openers of BK channels

Yong-Mei Cui, Eriko Yasutomi, Yuko Otani, Takashi Yoshinaga, Katsutoshi Ido, Kohei Sawada, Tomohiko Ohwada

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 263 KB

english, 2008

10

Novel oxime and oxime ether derivatives of 12,14-dichlorodehydroabietic acid: Design, synthesis, and BK channel-opening activity

Yong-Mei Cui, Eriko Yasutomi, Yuko Otani, Takashi Yoshinaga, Katsutoshi Ido, Kohei Sawada, Masatoshi Kawahata, Kentaro Yamaguchi, Tomohiko Ohwada

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 320 KB

english, 2008

11

Primary Liver Somatostatinoma

Susumu Ohwada, Takashi Joshita, Tsutomu Ishihara, Tetsunari Oyama, Yoshikazu Inui, Junichi Aoki

Journal:

Journal of Gastroenterology and Hepatology

Year:

2003

Language:

english

File:

PDF, 356 KB

english, 2003

12

Adenovirus vector-mediated transfer of 9 kDa granulysin induces DNA fragmentation in HuD antigen-expressing small cell lung cancer murine model cells

MITSUAKI SEKIYA, AKIHIKO OHWADA, MASAHARU KATAE, TAKASHI DAMBARA, ISAO NAGAOKA, YOSHINOSUKE FUKUCHI

Journal:

Year:

2002

Language:

english

File:

PDF, 408 KB

english, 2002

13

Increased circulating CD16+ CD14dim monocytes in a patient with pulmonary alveolar proteinosis

Yasuko YOSHIOKA, Akihiko OHWADA, Norihiro HARADA, Naotake SATOH, Shoko SAKURABA, Takashi DAMBARA, Yoshinosuke FUKUCHI

Journal:

Year:

2002

Language:

english

File:

PDF, 248 KB

english, 2002

14

CD4+ T cells in lung tissue predict responsiveness to cyclosporin A in interstitial pneumonia

YASUKO YOSHIOKA, AKIHIKO OHWADA, TAKASHI DAMBARA, YOSHINOSUKE FUKUCHI

Journal:

Year:

2002

Language:

english

File:

PDF, 64 KB

english, 2002

15

Small ileal neurofibroma causing intussusception in a non-neurofibromatosis patient

Fumio Watanuki, Susumu Ohwada, Yasuo Hosomura, Shinichi Okamura, Yoshiyuki Kawashima, Yoshifumi Tanahashi, Sciji Nakamura, Yuichi Iino, Takashi Johshita, Yasuo Morishita

Journal:

Journal of Gastroenterology

Year:

1995

Language:

english

File:

PDF, 1.23 MB

english, 1995

16

Immunohistochemical characterization of cell types expressing the cellular prion protein in the small intestine of cattle and mice

Kohtaro Miyazawa, Takashi Kanaya, Sachi Tanaka, Ikuro Takakura, Kouichi Watanabe, Shyuichi Ohwada, Haruki Kitazawa, Michael T. Rose, Suehiro Sakaguchi, Shigeru Katamine, Takahiro Yamaguchi, Hisashi As

Journal:

Histochemistry and Cell Biology

Year:

2007

Language:

english

File:

PDF, 912 KB

english, 2007

17

Apoptotic process of porcine intestinal M

Kohtaro Miyazawa, Hisashi Aso, Takashi Kanaya, Taketomo Kido, Takeshi Minashima, Kouichi Watanabe, Shyuichi Ohwada, Haruki Kitazawa, Michael T. Rose, Koji Tahara, Tadashi Yamasaki, Takahiro Yamaguchi

Journal:

Cell and Tissue Research

Year:

2006

Language:

english

File:

PDF, 582 KB

english, 2006

18

Down-regulation of hepatic stearoyl-CoA desaturase 1 expression by angiotensin II receptor blocker in the obesefa/faZucker rat: possible role in amelioration of insulin resistance and hepatic steatosis

Junji Yokozawa, Takashi Sasaki, Kumiko Ohwada, Yayoi Sasaki, Jun-Itsu Ito, Takafumi Saito, Sumio Kawata

Journal:

Journal of Gastroenterology

Year:

2009

Language:

english

File:

PDF, 239 KB

english, 2009

19

Ipsilateral femoral neck, shaft, and supracondylar fractures: a case report

Takashi Suzuki, Kazui Soma, Takashi Ohwada

Journal:

European Journal of Orthopaedic Surgery & Traumatology

Year:

2003

Language:

english

File:

PDF, 151 KB

english, 2003

20

Up-regulation of a BCL9-related β-catenin-binding protein, B9L, in different stages of sporadic colorectal adenoma

Ichiro Sakamoto, Susumu Ohwada, Hiroyuki Toya, Nozomi Togo, Kenji Kashiwabara, Tetsunari Oyama, Takashi Nakajima, Hideaki Ito, Shungo Adachi, Takafumi Jigami, Tetsu Akiyama

Journal:

Year:

2007

Language:

english

File:

PDF, 252 KB

english, 2007

21

Immunohistochemical expression of the β-catenin-interacting protein B9L is associated with histological high nuclear grade and immunohistochemical ErbB2/HER-2 expression in breast cancers

Hiroyuki Toya, Tetsunari Oyama, Susumu Ohwada, Nozomi Togo, Ichiro Sakamoto, Jun Horiguchi, Yukio Koibuchi, Shungo Adachi, Takafumi Jigami, Takashi Nakajima, Tetsu Akiyama

Journal:

Year:

2007

Language:

english

File:

PDF, 2.35 MB

english, 2007

22

Pancoast's syndrome in a patient with B-cell lymphoma diagnosed and confirmed with immunoglobulin gene rearrangement

Fumiyuki Takahashi, Akihiko Ohwada, Yoshie Higashihara, Yasuko Yoshioka, Toshimasa Uekusa, Kazuhisa Takahashi, Takashi Dambara, Yoshinosuke Fukuchi

Journal:

Year:

2004

Language:

english

File:

PDF, 140 KB

english, 2004

23

Blockade of bradykinin B2 receptor suppresses acute pancreatitis induced by obstruction of the pancreaticobiliary duct in rats

Mitsuhiro Hirata, Izumi Hayashi, Kuniko Yoshimura, Ken-ichiro Ishii, Kazui Soma, Takashi Ohwada, Akira Kakita, Masataka Majima

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 334 KB

english, 2002

24

Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage

Arai, Kiyomitsu, Morishita, Kazuhiro, Shinmura, Kazuya, Kohno, Takashi, Kim, Su-Ryang, Nohmi, Takehiko, Taniwaki, Masafumi, Ohwada, Susumu, Yokota, Jun

Journal:

Year:

1997

Language:

english

File:

PDF, 499 KB

english, 1997

25

Somatic mutations and genetic polymorphisms of the PPP1R3 gene in patients with several types of cancers

Takakura, Satoshi, Kohno, Takashi, Shimizu, Kimihiro, Ohwada, Susumu, Okamoto, Aikou, Yokota, Jun

Journal:

Year:

2000

Language:

english

File:

PDF, 226 KB

english, 2000

26

Induction mechanism of small intestinal lesions caused by intravenous injection of endotoxin in rats

Masateru Shindo, Masataka Majima, Takashi Ohno, Katsuhiko Sugimoto, Takashi Ohwada

Journal:

Year:

1996

Language:

english

File:

PDF, 1.47 MB

english, 1996

27

Pleomorphic Carcinoma of the Lung with Mediastinal Extension Following Malignant Lymphoma: Report of a Case

Takahiro Nakajima, Toshihiko Iizasa, Akira Iyoda, Kenzo Hiroshima, Kazuhiro Yasufuku, Masako Chiyo, Takashi Anayama, Hidemi Suzuki, Kiyoshi Shibuya, Hidemi Ohwada, Takehiko Fujisawa

Journal:

Year:

2005

Language:

english

File:

PDF, 230 KB

english, 2005

28

Fatal retropharyngeal haematoma secondary to blunt trauma

Takashi Suzuki, Hiroshi Imai, Masataka Uchino, Ryuji Wakita, Masataka Endo, Takao Kitahara, Kazui Soma, Takashi Ohwada

Journal:

Year:

2004

Language:

english

File:

PDF, 350 KB

english, 2004

29

Computerised tomography applied for orbital hypertelorism: A case report

Hiroshi Kamiishi, Takashi Ohwada, Nobuyuki Shioya

Journal:

British Journal of Plastic Surgery

Year:

1978

Language:

english

File:

PDF, 289 KB

english, 1978

30

Gluteal muscle necrosis following transcatheter angiographic embolisation for retroperitoneal haemorrhage associated with pelvic fracture

Naonobu Takahira, Masateru Shindo, Keiji Tanaka, Hiroshi Nishimaki, Takashi Ohwada, Moritoshi Itoman

Journal:

Year:

2001

Language:

english

File:

PDF, 328 KB

english, 2001

31

The diagnostic problem associated with blunt traumatic azygous vein injury: delayed appearance of right haemothorax after blunt chest trauma

Katsuhiko Sugimoto, Yasushi Asari, Mitsuhiro Hirata, Hiroshi Imai, Takashi Ohwada

Journal:

Year:

1998

Language:

english

File:

PDF, 2.15 MB

english, 1998

32

Frequent Chromosome 8q Gains in Human Small Cell Lung Carcinoma Detected by Arbitrarily Primed-PCR Genomic Fingerprinting

Tatsuya Yamada, Takashi Kohno, J.Manuel Navarro, Susumu Ohwada, Manuel Perucho, Jun Yokota

Journal:

Cancer Genetics and Cytogenetics

Year:

2000

Language:

english

File:

PDF, 342 KB

english, 2000

33

Orally Administered Prion Protein Is Incorporated by M Cells and Spreads into Lymphoid Tissues with Macrophages in Prion Protein Knockout Mice

Ikuro Takakura, Kohtaro Miyazawa, Takashi Kanaya, Wataru Itani, Kouichi Watanabe, Shyuichi Ohwada, Hitoshi Watanabe, Tetsuya Hondo, Michael T. Rose, Tsuyoshi Mori, Suehiro Sakaguchi, Noriyuki Nishida,

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 4.54 MB

english, 2011

34

Distinct Prognostic Factors in Patients with Chronic Heart Failure and Chronic Kidney Disease

Takamasa Sato, Tomofumi Misaka, Takashi Ohwada, Hiroyuki Yamauchi, Akiomi Yoshihisa, Hitoshi Suzuki, Shu-ichi Saitoh, Yasuchika Takeishi

Journal:

Journal of Cardiac Failure

Year:

2011

Language:

english

File:

PDF, 39 KB

english, 2011

35

Identification of bovine dendritic cell phenotype from bovine peripheral blood

Kohtaro Miyazawa, Hisashi Aso, Masashi Honda, Taketomo Kido, Takeshi Minashima, Takashi Kanaya, Kouichi Watanabe, Shyuichi Ohwada, Michael T. Rose, Takahiro Yamaguchi

Journal:

Research in Veterinary Science

Year:

2006

Language:

english

File:

PDF, 655 KB

english, 2006

36

Staining patterns for actin and villin distinguish M cells in bovine follicle-associated epithelium

Takashi Kanaya, Hisashi Aso, Kohtaro Miyazawa, Taketomo Kido, Takeshi Minashima, Kouichi Watanabe, Shyuichi Ohwada, Haruki Kitazawa, Michael T. Rose, Takahiro Yamaguchi

Journal:

Research in Veterinary Science

Year:

2007

Language:

english

File:

PDF, 2.82 MB

english, 2007

37

Expression of inflammatory-related factors in porcine anterior pituitary-derived cell line

Yasuhiro Nagai, Hideki Ogasawara, Yoshikazu Taketa, Hisashi Aso, Takashi Kanaya, Masato Miyake, Kouichi Watanabe, Shyuichi Ohwada, Yoshihiro Muneta, Takahiro Yamaguchi

Journal:

Veterinary Immunology and Immunopathology

Year:

2008

Language:

english

File:

PDF, 1.08 MB

english, 2008

38

Characteristics of pancreatic injury in children: A comparison with such injury in adults

Tsunemasa Takishima, Katsuhiko Sugimoto, Yasushi Asari, Takaaki Kikuno, Mitsuhiro Hirata, Akira Kakita, Takashi Ohwada, Kazuhiko Maekawa

Journal:

Journal of Pediatric Surgery

Year:

1996

Language:

english

File:

PDF, 534 KB

english, 1996

39

Effect of neutral endopeptidase inhibitor on bradykinin-induced bronchoconstriction

Yoshito Kamijo, Izumi Hayashi, Kazui Soma, Takashi Ohwada, Masataka Majima

Journal:

Year:

2001

Language:

english

File:

PDF, 184 KB

english, 2001

40

Dinitropyrenes induce gene mutations in multiple organs of the lambda/lacZ transgenic mouse (Muta™ Mouse)

Arihiro Kohara, Takayoshi Suzuki, Masamitsu Honma, Takashi Oomori, Tomohiko Ohwada, Makoto Hayashi

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2002

Language:

english

File:

PDF, 351 KB

english, 2002

41

Relation between myocardial damage and noradrenergic activities in the central and peripheral nervous systems in patients with subarachnoid hemorrhage

Shinichiro Yamamoto, Takashi Masuda, Narihisa Matsuyama, Kiyotaka Sato, Koh-ichiro Okuhara, Chiharu Noda, Kazuko Murakami, Takashi Ohwada

Journal:

Journal of the American College of Cardiology

Year:

1996

Language:

english

File:

PDF, 146 KB

english, 1996

42

Rapid enlargement of ventricles within seven hours after head injury

Hiroshi Takagi, Yoshio Tamaki, Seiji Morii, Takashi Ohwada

Journal:

Surgical Neurology

Year:

1981

Language:

english

File:

PDF, 1.83 MB

english, 1981

43

Correlation between intravascular pressure and risk of hemorrhage due to arteriovenous malformations

Yoshio Miyasaka, Kenzoh Yada, Akira Kurata, Kaichi Tokiwa, Katsumi Irikura, Ryusui Tanaka, Takashi Ohwada, Takao Kitahara

Journal:

Surgical Neurology

Year:

1993

Language:

english

File:

PDF, 297 KB

english, 1993

44

The effects of a carotid-jugular fistula on cerebral blood flow in the cat: An experimental study in the acute period

Yoshio Miyasaka, Kaichi Tokiwa, Katsumi Irikura, Akira Kurata, Ryusui Tanaka, Seiji Morii, Kenzoh Yada, Takao Kitahara, Takashi Ohwada

Journal:

Surgical Neurology

Year:

1994

Language:

english

File:

PDF, 281 KB

english, 1994

45

P1F152 - Successful treatment of cibenzoline succinate poisoning using direct hemoperfusion (DHP)

Rumiko Kondo, Naoyoshi Aoyama, Takeshi Sasaki, Makoto Yoshida, Keisuke Suzuki, Yoshito Kamijo, Yasushi Asari, Kazui Soma, Tohru Izumi, Takashi Ohwada

Journal:

Toxicology Letters

Year:

1998

Language:

english

File:

PDF, 133 KB

english, 1998

46

Subject index

Ido, Katsutoshi, Ohwada, Tomohiko, Yasutomi, Eriko, Yoshinaga, Takashi, Arai, Tohru, Kato, Mitsuyasu, Sawada, Kohei

Journal:

Year:

1978

Language:

english

File:

PDF, 385 KB

english, 1978

47

Screening quality for Ca2+-activated potassium channel in IonWorks Quattro is greatly improved by using BAPTA-AM and ionomycin

Ido, Katsutoshi, Ohwada, Tomohiko, Yasutomi, Eriko, Yoshinaga, Takashi, Arai, Tohru, Kato, Mitsuyasu, Sawada, Kohei

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2013

Language:

english

File:

PDF, 969 KB

english, 2013

48

Synthesis of gefarnate with reusable lipase modified with polyethylene glycol

Mizutani, Akemi, Takahashi, Katsunobu, Aoki, Takashi, Ohwada, Kimiko, Kondo, Kiyosi, Inada, Yuji

Journal:

Journal of Biotechnology

Year:

1989

Language:

english

File:

PDF, 236 KB

english, 1989

49

Survival After Massive Arsenic Poisoning Self-Treated by High Fluid Intake

Kamijo, Yoshito, Soma, Kazui, Asari, Yasushi, Ohwada, Takashi

Journal:

Clinical Toxicology (Informa Healthcare)

Year:

1998

Language:

english

File:

PDF, 105 KB

english, 1998

50

Alkaline Esophagitis Evaluated by Endoscopic Ultrasound

Kamijo, Yoshito, Kondo, Ichiei, Soma, Kazui, Imaizumi, Hiroshi, Ohwada, Takashi

Journal:

Clinical Toxicology (Informa Healthcare)

Year:

2001

Language:

english

File:

PDF, 137 KB

english, 2001